منابع مشابه
Optimal Design of Experimental Epidemics
We consider the optimal design of experimental epidemics modelled as density dependent Markov processes. We focus on finding (i) the optimal times at which to collect data about the state of the system for a small number of discrete observations, (ii) the optimal numbers of susceptible and infective individuals to begin an experiment with, and (iii) the optimal number of replicate epidemics to ...
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متن کاملTitle Population (and Individual) Optimal Experimental Design
March 20, 2015 Type Package Title Population (and Individual) Optimal Experimental Design Version 0.2.0 Depends ggplot2 Imports MASS, mvtnorm, nlme, dplyr, codetools Suggests testthat, Hmisc Description Optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix (FIM). This ...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2018
ISSN: 1548-7091,1548-7105
DOI: 10.1038/s41592-018-0083-2